Dry Age-related Macular Degeneration Seven Major Market to Exhibit Growth at a CAGR of 19.8% by 2034 | DelveInsight
Key Takeaways from the Dry Age-related Macular Degeneration Market Report
Discover which therapies are expected to grab the major dry AMD market share @ Dry Age-related Macular Degeneration Market Report
Dry Age-related Macular Degeneration Overview
Dry AMD, a prevalent ocular condition affecting individuals aged 50 and above, leads to a decline in central vision clarity due to macular thinning. The macula, essential for sharp vision in the central field, is affected. Typically, dry AMD progresses slowly, often without causing discomfort or noticeable symptoms for years. Symptoms may include difficulty seeing in low light, distorted straight lines, altered color perception, and gradual vision changes. Dry AMD advances through early, intermediate, and advanced stages, the latter also termed "geographic atrophy," which affects the fovea. Diagnosis involves a thorough eye examination by an ophthalmologist or optometrist, identifying characteristic signs like drusen, yellow deposits beneath the retina, and pigmentation alterations.
Dry Age-related Macular Degeneration Epidemiology Segmentation
Among the 7MM, the US accounted for the highest prevalent cases of dry AMD in 2023, with over 21 million cases; these cases are expected to increase during the forecast period.
According to the estimates, in Asian countries, the prevalence of geographic atrophy is low.
It has been reported that the prevalence of late-stage AMD increases with age. In Japan, it is observed that age-specific cases of geographic atrophy were most prevalent in the 85+ years age group, accounting for over 40% of total cases in 2023.
The dry AMD market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into:
Dry Age-related Macular Degeneration Treatment Market
The therapeutic landscape of intermediate AMD is devoid of any approved treatment, and to manage this indication, there is a substantial unmet need for therapy to slow its worsening. The current approach revolves around dietary vitamins and supplements. Recommendations for patients affected by intermediate AMD are focused on the correction of risk factors, especially quitting smoking, following a healthy diet, and treating concomitant diseases such as hypertension, obesity, and atherosclerosis. Identifying early biomarkers for AMD progression is crucial for personalized management and timely intervention.
According to the National Eye Institute (2020), individuals with geographic atrophy may find benefits from enhanced lighting, magnification aids, and low-vision tools to aid in reading. Additionally, some patients may opt for an implantable miniature telescope, which is surgically placed in the eye to replace the lens. By enlarging images, this device can assist specific, carefully chosen patients with either near or distant vision. Unlike neovascular AMD (n-AMD), which is characterized by sudden vision loss and often shows improvement in both structure and function after treatment, geographic atrophy progresses slowly and steadily, eventually leading to irreversible vision loss.
Until recently, there were no established treatments available for geographic atrophy. However, in 2023, the FDA approved SYFOVRE in February and IZERVAY in August to retard the advancement of geographic atrophy lesions. Although injections of IZERVAY or SYFOVRE can decelerate the progression of the disease, it is crucial to understand that they cannot reverse its effects or recover lost vision.
To know more about dry AMD treatment guidelines, visit @ Dry Age-related Macular Degeneration Management
Dry Age-related Macular Degeneration Pipeline Therapies and Key Companies
Learn more about the FDA-approved drugs for dry AMD @ Drugs for Dry Age-related Macular Degeneration Treatment
Dry Age-related Macular Degeneration Market Dynamics
The dynamics of the dry AMD market are expected to change in the coming years. The dry AMD market has a miscellaneous pipeline, including peptide derivatives, antibodies, antisense oligonucleotides, stem cell therapy, and gene therapy, which work on different mechanisms such as C1q, C3, and C5 Inhibitors, cell replacements, HtrA Serine Peptidase 1 inhibitors, and others. This dry AMD market remains untapped, with a large and increasing patient pool.
Furthermore, many potential therapies are being investigated for the treatment of dry AMD, and it is safe to predict that the treatment space will significantly impact the dry AMD market during the forecast period. Moreover, the anticipated introduction of emerging therapies with improved efficacy and a further improvement in the diagnosis rate are expected to drive the growth of the dry AMD market in the 7MM.
As new drugs are expected to receive approval from regulators after 2025–2027, it will be interesting to follow how the landscape of Dry AMD, particularly geographic atrophy, changes. At this point, no medication is now on the cusp of approval and poses an immediate threat to SYFOVRE or IZERVAY.
However several factors may impede the growth of the dry AMD market. There is a lack of validated endpoint which may hamper the advancement of the therapies and to show their clinical benefits; most of the emerging therapies are targeting geographic atrophy, and this might impact the uptake of emerging drugs owing to anticipated intense competition in the same segment, while emerging gene therapies and stem cell therapies for dry AMD may face hurdles in access and reimbursement due to its anticipated high cost.
Moreover, dry AMD treatment poses a significant economic burden and disrupts patients' overall well-being and QOL. Furthermore, the dry AMD market growth may be offset by failures and discontinuation of emerging therapies, and a shortage of healthcare specialists. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the dry AMD market growth.
Scope of the Dry Age-related Macular Degeneration Market Report
Discover more about dry AMD drugs in development @ Dry Age-related Macular Degeneration Clinical Trials
Table of Contents
Related Reports
Dry Age-related Macular Degeneration Pipeline
Dry Age-related Macular Degeneration Pipeline Insight – 2024 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key dry AMD companies, including Alkeus Pharmaceuticals, Dobecure, Iveric Bio, Mitotech, Stealth BioTherapeutics, Allergo Ophthalmics, Gyroscope Therapeutics, Gemini Therapeutics, Luxa Biotechnology, CHABiotech CO., Ltd, Regenerative Patch Technologies, Lineage Cell Therapeutics, Janssen Research & Development, Belite Bio, Katairo, Cognition Therapeutics, Eye Co Pty Ltd, Applied Genetic Technologies Corporation (AGTC), Aviceda Therapeutics, Kodiak Sciences, Ascentage Pharma, OliX Pharmaceutical, Nanoscope Therapeutics, Inc., Biophytis, Eyestem, Eyevensys, SanBio, Beta Therapeutics, MacRegen, Amarna Therapeutics, MeiraGTx, Cognition Therapeutics, Ocugen, Catalyst Biosciences, Endogena Therapeutics, Oculogenex, Clover Therapeutics, Retrotope, Stuart Therapeutics, Surrozen, 4D Pharma, Ocular Therapeutix, among others.
Dry Age-related Macular Degeneration Epidemiology Forecast
Dry Age-related Macular Degeneration Epidemiology Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted dry AMD epidemiology in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan.
Age-related Macular Degeneration Market
Age-related Macular Degeneration Market Insights, Epidemiology, and Market Forecast – 2034 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, market share of the individual therapies, and key AMD companies including Regeneron Pharmaceuticals, Novartis, Roche, Opthea Limited, Kodiak Sciences Inc., REGENXBIO, Alkahest Inc, Graybug Vision, Ribomic USA Inc, Outlook Therapeutics, Inc., Unity Biotechnology, Inc, PanOptica, Inc., Clearside Biomedical, Alexion Pharmaceuticals, AstraZeneca, Evergreen Therapeutics, Alkeus Pharmaceuticals, Stealth BioTherapeutics, CellCure Neurosciences, Regenerative Patch Technologies, Allegro Ophthalmics, Annexon Biosciences, NGM Biopharmaceuticals, Ionis Pharmaceuticals, Apellis Pharmaceuticals, Iveric Bio, Gyroscope Therapeutics, Luxa Biotechnology, Gemini Therapeutics, among others.
Wet Age-related Macular Degeneration Market
Wet Age-related Macular Degeneration Market Insights, Epidemiology, and Market Forecast – 2034 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key Wet Age-related Macular Degeneration companies including EyePoint Pharmaceuticals, Inc., AbbVie, Caregen Co. Ltd., Exegenesis Bio, Shanghai Henlius Biotech, Skyline Therapeutics, 4D Molecular Therapeutics, Ocugenix Corporation, Adverum Biotechnologies, Inc., Ashvattha Therapeutics, Inc., AiViva BioPharma, Inc., Ocular Therapeutix, Inc., Clearside Biomedical, Inc., Hoffmann-La Roche, Kyowa Kirin, Inc., Opthea Limited, AffaMed Therapeutics Limited, EyeBiotech Ltd., Novartis, among others.
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.
Contact Us
Shruti Thakur
[email protected]
+14699457679
www.delveinsight.com
View original content:https://www.prnewswire.co.uk/news-releases/dry-age-related-macular-degeneration-seven-major-market-to-exhibit-growth-at-a-cagr-of-19-8--by-2034--delveinsight-302122968.html
