Malattia di Charcot-Marie-Tooth

La malattia di Charcot-Marie-Tooth o CMT o Hereditary Motor and Sensory Neuropathy (HMSN), nota anche come Neuropatia motorio-sensitiva ereditaria, è una sindrome neurologica ereditaria a carico del sistema nervoso periferico. Deve il suo nome ai tre medici che per primi la descrissero: Jean-Martin Charcot, Pierre Marie, e Howard Henry Tooth. Con il nome CMT sono indicate molte malattie, con sintomi anche estremamente diversi, la forma di gran lunga più diffusa è la 1A, che si caratterizza per perdita di tono muscolare e della sensibilità al tatto, in particolare agli arti inferiori al di sotto del ginocchio; meno frequentemente, e in genere negli stadi più avanzati della malattia, gli effetti si notano anche negli arti superiori al di sotto del gomito. Allo stato attuale non esistono cure, sebbene la CMT sia la malattia più diffusa tra le sindromi neurologiche ereditarie, con 36 casi di insorgenza ogni 100.000 nascite. In Italia è classificata dal Ministero della Sanità come malattia rara. Può essere associata al diabete mellito. (fonte: Wikipedia)
Comunicati Stampa

Addex Raises CHF2.8 million in a Private Placement and Extends Cash Runway Through 2017

Addex Therapeutics / Addex Raises CHF2.8 million in a Private Placement and Extends Cash Runway Through 2017 . Processed and transmitted by NASDAQ OMX Corporate Solutions. The issuer is solely responsible for the content of this announcement. Geneva, Switzerland, 9 March 2015 - Addex Therapeutics (SIX: ADXN) announced today that it has raised gross proceeds of CHF2.8 million in a private placement of new issued registered shares... (Thomson Reuters - 09/03/2015) Leggi

Botulism Therapeutics PipelineReview H1 2015 Market Research Report

The report "Botulism - Pipeline Review, H1 2015" provides comprehensive information on the therapeutic development for botulism. Botulism is an unusual but serious condition caused by toxins from germs. There are four clinical types of botulism: foodborne, wound, infant and adult colonization botulism. Botulism develops if a person ingests the toxin or if the organism grows in the bowels or wounds and toxin is released. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. (PR Newswire - 03/02/2015) Leggi

Addex Completes 2014 with Strong Cash Position and Provides 2015 Strategic Update

Addex Therapeutics / Addex Completes 2014 with Strong Cash Position and Provides 2015 Strategic Update . Processed and transmitted by NASDAQ OMX Corporate Solutions. The issuer is solely responsible for the content of this announcement. Geneva, Switzerland, 9 January 2015 - Addex Therapeutics (SIX: ADXN), a leading company pioneering allosteric modulation-based drug discovery and development announced today: Financial Update Addex completed 2014 with cash and cash... (Thomson Reuters - 09/01/2015) Leggi

Pharnext's Pleotherapy Shows Synergistic Effects with PXT-864 in Alzheimer's Disease through Preclinical Data Published in Nature's Scientific Reports

PARIS, Jan. 8, 2015 /PRNewswire/ -- Pharnext SAS today announced the publication of preclinical results in Nature's Scientific Reports for its lead pleodrug, PXT-864, in Alzheimer's disease. These data further validate its pleotherapy research and development approach based on a proprietary network pharmacology platform that identifies synergic combinations of drugs already approved for other diseases. (PR Newswire - 08/01/2015) Leggi

La pleoterapia de Pharnext muestra efectos sinérgicos con PXT-864 en la enfermedad de Alzheimer

- Los datos preclínicos ofrecen más validación del enfoque de pleoterapia de Pharnext (PR Newswire - 08/01/2015) Leggi
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Altri nomi: CMT, Morbus Charcot-Marie-Tooth, Hereditary motor and sensory neuropathy, Charcot-Marie-Tooth neuropathy, Hereditary sensory motor neuropathy, Peroneal muscular atrophy, Hereditary sensorimotor neuropathy, HSMN, Charcot-Marie-Tooth disorder