ABLYNX ANNOUNCES 2016 HALF-YEAR RESULTS AND YEAR-TO-DATE BUSINESS UPDATE

REGULATED INFORMATION Very important clinical pipeline developments and a successful financingConference call and webcasttoday at 4pm CET/10am ET GHENT, Belgium, 25 August 2016 - Ablynx[Euronext Brussels: ABLX; OTC: ABYLY] today announced its financial results for the...

London, 25/08/2016 (informazione.it - comunicati stampa - salute e benessere)

Conference call and webcast

today announced its financial results for the six-month period ending 30 June 2016, which have been prepared in accordance with the IAS 34 "Interim Financial Reporting" as adopted by the European Union, a business update for the year-to-date and the outlook for the next period.

"It has been a hugely productive year so far for us," . "We successfully completed three clinical trials in RSV and RA and the results provide an excellent platform for the continued development of both ALX-0171 and vobarilizumab. With ALX-0171, we are now preparing for a worldwide Phase II efficacy study in hospitalised infants with an RSV infection which is expected to start before the end of the year. The Phase IIb data for vobarilizumab give us great confidence that the molecule should move into Phase III development as soon as possible. We are now preparing the complete data package from the Phase IIb vobarilizumab studies for AbbVie and we expect them to decide before the end of the year if they wish to opt-in and license the product for RA. In parallel, we are starting preparations for a Phase III programme with vobarilizumab in RA and we plan to move forward with this in the event AbbVie do not opt-in, while then at the same exploring new relationships which will allow us to maximize the potential of this exciting drug candidate."

"We continued to make good progress in our most advanced clinical programme, where we are developing caplacizumab for the treatment of acquired TTP, and are on track to file the dossier for conditional approval in Europe early next year. Recruitment for the HERCULES Phase III trial with caplacizumab in acquired TTP patients is proceeding well and we now intend to increase the power of the key secondary efficacy endpoint by recruiting about 40% more patients than originally planned while still aiming to meet our original goal to report the study results before the end of 2017."

"Our R&D pipeline is developing very encouragingly and now includes more than 45 proprietary and partnered programmes. Three new programmes entered clinical development with our partners and >15 new wholly-owned and partnered discovery programmes have been initiated since the beginning of the year, demonstrating our commitment to continue to fuel our product pipeline."

"In June, we further strengthened our cash position through a €74.2 million (gross) oversubscribed private placement of new shares with existing and new investors, and we remain focused on delivering sustainable value to all our stakeholders."

         
        Excluding €71.4 million net proceeds from the private placement of new shares (1 June 2016)
        Excluding €97.2 million net proceeds from the convertible bond (20 May 2015)
        Including €1.3 million in restricted cash
        Including €1.6 million restricted cash
* Defined as liquidity position in the cash flow statement

Ablynx is a biopharmaceutical company engaged in the development of Nanobodies®, proprietary therapeutic proteins based on single-domain antibody fragments, which combine the advantages of conventional antibody drugs with some of the features of small-molecule drugs. Ablynx is dedicated to creating new medicines which will make a real difference to society. Today, the Company has more than 45 proprietary and partnered programmes in development in various therapeutic areas including inflammation, haematology, immuno-oncology, oncology and respiratory disease. The Company has collaborations with multiple pharmaceutical companies including AbbVie, Boehringer Ingelheim, Eddingpharm, Genzyme, Merck & Co., Inc., Merck KGaA, Novartis, Novo Nordisk and Taisho Pharmaceuticals. The Company is headquartered in Ghent, Belgium. More information can be found on www.ablynx.com.

Dr Edwin Moses
CEO
t:   +32 (0)9 262 00 07
m: +32 (0)473 39 50 68
e:  edwin.moses@ablynx.com

Marieke Vermeersch
Director IR & Corporate Communications
t:   +32 (0)9 262 00 82
m: +32 (0)479 49 06 03
e:  marieke.vermeersch@ablynx.com
Follow us on Twitter @AblynxABLX

Julia Phillips, Brett Pollard, Mo Noonan, Matthew Moss
t: +44 20 3727 1000
e: ablynx@fticonsulting.com